Ghana is the second largest producer of cocoa in the world supplying 25% of the world’s cocoa, thus cocoa production contributes significantly to the economy of Ghana. The average national annual yield (350 kg/ha) in Ghana is very small compared to 800 kg/ha in Côte d'Ivoire, and 1700 kg/ha in Malaysia. This has been attributed to low adoption and inappropriate application of innovations by cocoa farmers. Despite the fact that Cocoa Research Institute of Ghana (CRIG) had conducted various on-farm research resulting in yields averaging about 13,000kg/ha in 1991, the innovations had not been fully extended to the estimated 500,000 cocoa farmers in Ghana. In 2003, the government of Ghana introduced the Cocoa High Technology Programme (CHTP) with the aim of improving the fertility of the soil by applying a newly developed fertilizer and other technologies to existing cocoa farms to increase the productivity of the farms. A survey of 200 cocoa farmers, who had adopted the technology in the Eastern Region of Ghana in 2006, was conducted with the aim of estimating how effective cocoa farmers had applied the main components of the CHTP. The results showed that none of the farmers did soil testing before fertiliser application. Although almost all (99.5%) the farmers applied the fertiliser, they did not use the prescribed ring-method of application that ensures that each cocoa tree has optimal amount of nutrient needed. Barely half (42%) of the farmers applied it on the recommended time. Main reasons given for the farmers’ inability to use the precision that came with the CHTP include lack of awareness of the need to perform soil testing, late distribution of fertilizers to farmers and inadequate training of farmers on the precise methods of applying the technologies. The aforesaid constraints, among others, militated against the achievement of the target set by the programme. Several recommendations were made which could make precision agriculture feasible in the cocoa industry in Ghana and other cocoa producing countries.